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Microtomes: A Guide to Precision Cutting in Scientific Research

Microtomes are essential tools in scientific research, used for precision cutting of thin sections of biological and materials samples for examination under a microscope. They come in different types and sizes, each with unique features that make them suitable for specific applications. In this guide, we will explore the different types of microtomes and their uses.

Rotary Microtomes

Rotary microtomes are the most common type of microtome. They work by rotating a sample block against a stationary blade to produce thin sections. They are ideal for cutting soft tissues, such as brain and liver samples. Rotary microtomes come in manual and automated versions, with the latter being more efficient and precise.

Cryostats

Cryostats are specialized microtomes used for cutting frozen samples. They work by freezing the sample block and then cutting it while it is still frozen. Cryostats are ideal for cutting samples that are difficult to section when they are at room temperature, such as fatty tissues. They are also used for cutting samples that need to be analyzed quickly, such as in emergency pathology.

Vibratomes

Vibratomes are microtomes that use a vibrating blade to cut thin sections. They are ideal for cutting delicate samples, such as brain slices, that are difficult to cut with a rotary microtome. Vibratomes are also used for cutting samples that need to be kept in their natural state, such as plant tissues.

Conclusion

Microtomes are essential tools in scientific research, used for precision cutting of thin sections of biological and materials samples. The type of microtome used depends on the nature of the sample and the desired outcome. Rotary microtomes are the most common type of microtome and are ideal for cutting soft tissues. Cryostats are used for cutting frozen samples, while vibratomes are used for cutting delicate samples. Investing in a high-quality microtome is essential for achieving accurate and reliable results in scientific research.

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Trending: Microtomes

United Scientific MCT001 Hand Microtome

United Scientific MCT001 Hand Microtome

Brand, Category: United Scientific Supplies Science Education
Price Range: $51.59
Rating: 3/5

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United Scientific MCT001 Hand Microtome Review

The United Scientific MCT001 Hand Microtome is a great tool for those looking to prepare simple items on microscope slides. Here are some pros and cons to consider before purchasing:

Pros:

  • Easy to use for beginners.
  • Compact design for easy storage.

Cons:

  • May not be suitable for more advanced laboratory work.
  • Photo on Amazon may be misleading and require further research to properly use.


    Economy Simple Hand Microtome Without Box

    Economy Simple Hand Microtome Without Box

    Brand, Category: 3B Scientific 0
    Price Range: $25.95
    Rating: 4.5/5

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    Pros:

    • Easy to use and produces thin sections for microscopy.
    • Made of durable materials and built to last.

    Cons:

    • May not be suitable for those looking for more advanced slicing capabilities.
    • Lack of storage box may be inconvenient for some users.

    Overall, the Economy Simple Hand Microtome is a great basic tool for microscopy enthusiasts and beginners alike. Just be aware of its limitations before purchasing.


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    Featured Brands for Microtomes

    Find Top Brands for Microtomes including United Scientific Supplies, Science First, LabStorage, Radical, Electron Microscopy Sciences and more.

    • Microtomic
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